Professor Ailsa Hart

Consultant Gastroenterologist / Sub-Dean (St Mark’s Academic Institute)

BA (Hons) BMBCh FRCP PhD

Contact

NHS Medical Secretary:

Rupa Guedes

Tel: 020 8869 5808 Email: rupa.guedes@nhs.net

Professor Ailsa Hart

BA (Hons) BMBCh FRCP PhD

Consultant Gastroenterologist / Sub-Dean (St Mark’s Academic Institute)

Professor Ailsa Hart trained in medicine at Oxford University and was awarded a First Class Honours Degree in 1992 and the George Pickering Prize for Medicine and Surgery Proxime Accessit in 1995 and prizes for outstanding achievements. She achieved Membership of the Royal College of Physicians in 1998 and trained in Gastroenterology and General Internal Medicine in London. She also worked at the Academic Medical Centre in Amsterdam in 2004. She achieved her PhD in 2005 with Imperial College, London funded by a Wellcome Trust Fellowship. She became a Fellow of the Royal College of Physicians in 2013.

She was appointed to the consultant staff of St Mark’s Hospital in 2008 and became a Clinical Senior Lecturer at Imperial College London, having been awarded a highly competitive Clinical Senior Lectureship by the Higher Education Funding Council for England. She is currently Director of St Mark’s Hospital Inflammatory Bowel Disease Unit, which has around 5000 patients, and Honorary Senior Clinical Lecturer at Imperial College.

Her clinical work covers the spectrum of gastrointestinal diseases, with a particular interest in inflammatory bowel diseases (Crohn’s disease and ulcerative colitis). Her research interests focus on intestinal immunology and bacteriology aiming to further our understanding of the pathogenesis of inflammatory intestinal disorders.

She combined a busy clinical practice with research, both clinical trials in IBD and translational research. In particular at St Mark’s, she runs the “Fistula Research Group”, the “Pouch Research Group” and the “CRC surveillance Research Group”. She links with laboratories within Imperial College, particularly the Antigen Presentation Research Group, whose focus is on human intestinal dendritic cells and their role in homing and compartmentalisation of the immune response. She has piloted faecal transplantation as a treatment for refractory pouchitis funded by the Eli and Edyth Broad Foundation. She is coordinator of the British Society of Gastroenterology “Gut Microbiota for Health” Expert Panel and a member of Imperial College “Centre of Digestive and Gut Health”.

She is involved in teaching and training both nationally and internationally and has lectured by invitation at over 200 meetings. Her research work led to the publishing of two books, with “Inflammatory Bowel Disease – an Evidence-based Practical Guide” selling over 2500 copies and being a best seller at national and international meetings. She has also published over 100 papers and book chapters. She is a member of national and international IBD committees and consensus groups.

She has received a number of awards including first prize in an “Emerging Leaders in Gastroenterology” competition, the Novartis Foundation bursary and prizes awarded by the British Society of Gastroenterology and the United European Gastroenterology Society for outstanding research contributions. She is one of five members of the Clinical Committee of the European Crohn’s and Colitis Organisation (ECCO); on the IBD (inflammatory bowel disease) Committee for the British Society of Gastroenterology, UK Patient and Public Involvement Lead for Gastroenterology for the CRN; Sub-Dean of St Mark’s Hospital; and collaborates widely across the UK particularly within the UK IBD Genetics Consortium.

She was elected onto the International Organisation for the study of IBD (IOIBD) in 2014. The IOIBD, whose aim is to promote the health of those with IBD worldwide, is the only international organisation dedicated to the study of these illnesses. The IOIBD’s mission statement is to “promote the health of people with IBD worldwide by setting the direction for patient care, education and research.” This is a highly prestigious appointment, as only 50 physicians and surgeons worldwide have been elected onto this organisation.

Her clinical work centres on inflammatory bowel diseases (IBD), Crohn’s disease, and ulcerative colitis. She is credited for “putting St Mark’s on the global map” for IBD and being a “brilliant advocate for British IBD”. At an early stage in her consultant career, she was made Director of St Mark’s Hospital IBD Unit, and alongside an excellent team has developed and delivered a world-class clinical service with joint medical/ surgical clinics, new diagnosis clinics, biologics/ advanced therapy clinics and a psychological medicine unit for IBD.

She interdigitates a busy clinical practice with research. Her research interests demonstrate breadth and depth from basic science (understanding intestinal immunology and microbiology) to holistic care of IBD. She is Co-Director of a global consortium, TOp Class (Treatment Optimisation and Classification) for perianal Crohn’s disease, publishing a new classification for this challenging phenotype of IBD. She conducted among the first trials of faecal transplantation in IBD and has an ongoing research interest in the gut microbiome. She has a long-lasting collaboration aiming to optimise colorectal cancer surveillance for IBD patients, using the St Mark’s largest and longest running database as the backbone for the research. She has been gastroenterology lead for the IBD BOOST programme, which is developing psychological therapies for fatigue, pain and continence issues in IBD.

She has published 2 books and over 300 papers. Her h-index is 63.

She has supervised and mentored over 30 higher degree students, many of whom are now directing their own IBD units. She lectures widely nationally and internationally. She has delivered the Sir Arthur Hurst Lecture, the highest accolade bestowed by the BSG, and has been Visiting Professor in Australia, USA, Canada, India, UAE, Africa, Scandinavia and Europe.

She has contributed to national (British Society of Gastroenterology) and international societies (European Crohn’s and Colitis Organisation for over 10 years, serving on its Governing Board for 6 years; United European Gastroenterology Faculty; and the International Organisation of IBD) throughout her consultant career. She has been Chair of the BSG Gut Microbiota for Health Group; Member of the IBD Clinical Research Group Committee for the BSG; Member of the Clinical Committee of the ECCO; Treasurer of ECCO; Scientific Officer of ECCO (steering through the pandemic years); author of BSG and ECCO guidelines; Editorial Board of Alimentary Pharmacology and Therapeutics and Journal of Crohn’s and Colitis; UK Patient and Public Involvement & Engagement Lead for Gastroenterology; Research Committee Member and patient information writer for the Crohn’s and Colitis UK charity. She was elected to the International Organisation for IBD (IOIBD), which is a group of approximately 50 top clinicians globally involved in IBD – she is only one of three members from the UK and the only UK woman involved